CD137 (4-1BB) Monoclonal Antibody (4B4-1) | Invitrogen MA5-28559 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD137 (4-1BB) Monoclonal Antibody (4B4-1)

catalog :

MA5-28559

quantity :

100 ug

price :

US 169.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4B4-1

The same clone is also sold as:

Bio-Rad: MCA6117, MCA6117APC
Abcam: ab234169
Exbio: 11-143-C100, 1P-143-T025, 1P-143-T100, 12-143-C100, 11-143-C025, 1A-143-T100
BD Biosciences: 555956, 552533, 550890, 555955, 561702
BioLegend: 309826, 309827, 309818, 309824, 309813, 309821, 309825, 309806, 309816, 309839, 309850, 309814, 309808, 309853, 309837, 309841, 309829, 309810, 309822, 309849, 309819, 309834, 309848, 309847, 309832, 309852, 309828, 309842, 309830, 309831, 309851, 309843, 309835, 309845, 309833, 309817, 309820, 309802, 309823, 309803, 309804, 309809, 309844

reactivity :

crab eating macaque, baboon , human, chimpanzee, rhesus macaque

application :

immunoprecipitation, flow cytometry

product information

Product Type :

Antibody

Product Name :

CD137 (4-1BB) Monoclonal Antibody (4B4-1)

Catalog # :

MA5-28559

Quantity :

100 ug

Price :

US 169.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Baboon, Chimpanzee, Cynomolgus Monkey, Human, Non-human primate, Rhesus Monkey

Applications :

ELISA: Assay-Dependent, Flow Cytometry: 1-4 ug/mL, Functional Assay: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Species :

Baboon, Chimpanzee, Cynomolgus Monkey, Human, Non-human primate, Rhesus Monkey

Clone :

4B4-1

Isotype :

IgG1, kappa

Storage :

4 C, do not freeze

Description :

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.

Immunogen :

Recombinant human CD137 ectodomain

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Flow Cytometry: 1-4 ug/mL, Functional Assay: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Aliases :

4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9