CD61 (Integrin beta 3) Monoclonal Antibody (JM2E5), FITC | Invitrogen MA5-28415 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD61 (Integrin beta 3) Monoclonal Antibody (JM2E5), FITC

catalog :

MA5-28415

quantity :

100 ug

price :

US 728.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

JM2E5

The same clone is also sold as:

Bio-Rad: MCA2263F

reactivity :

pigs

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

CD61 (Integrin beta 3) Monoclonal Antibody (JM2E5), FITC

Catalog # :

MA5-28415

Quantity :

100 ug

Price :

US 728.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Porcine

Applications :

Flow Cytometry: Neat-1:10

Species :

Porcine

Clone :

JM2E5

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles. Store in the dark.

Description :

CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectrin. CD61 is a 105 kDa glycoprotein that associates with either the alpha 11b integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, Von Willebrand Factor, vitronectin and thrombospondin. The CD61 protein product is composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. CD61 is found along with the alpha IIb chain in platelets. Like other integrins, CD61 is known to participate in cell adhesion as well as cell-surface mediated signaling. Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.

Immunogen :

Porcine peripheral blood mononuclear cells

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Neat-1:10

Aliases :

antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa