TIM-4 Monoclonal Antibody (RMT4-54) | Invitrogen MA5-28256 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TIM-4 Monoclonal Antibody (RMT4-54)

catalog :

MA5-28256

quantity :

100 ug

price :

US 332.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

RMT4-54

The same clone is also sold as:

Bio X Cell: BE0225-1MG, BE0225-5MG, BE0225-50MG, BE0225-100MG, BE0225-25MG
Bio-Rad: MCA5791GA
BioLegend: 130013, 130005, 130016, 130025, 130009, 130008, 130020, 130021, 130022, 130011, 130002, 130019, 130017, 130015, 130014, 130006, 130018, 130010, 130023, 130007
OriGene: AM60019PU-S

reactivity :

mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 2

Reference
Aguilar Brise xf1 o J, Elliff J, Patten J, Wilson L, Davey R, Bailey A, et al. Effect of Interferon Gamma on Ebola Virus Infection of Primary Kupffer Cells and a Kupffer Cell Line. Viruses. 2023;15: pubmed publisher
Imperatore F, Maurizio J, Vargas Aguilar S, Busch C, Favret J, Kowenz Leutz E, et al. SIRT1 regulates macrophage self-renewal. EMBO J. 2017;36:2353-2372 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TIM-4 Monoclonal Antibody (RMT4-54)

Catalog # :

MA5-28256

Quantity :

100 ug

Price :

US 332.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1:25-1:200, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent

Species :

Mouse

Clone :

RMT4-54

Isotype :

IgG2a

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

Immunogen :

Tim-4-Ig, consisting of amino acids 1-288 of mouse Tim-4, coupled with the Fc portion of mouse IgG2a

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:25-1:200, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent

Aliases :

B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4