H3.3 K27M oncohistone mutant Recombinant Rabbit Monoclonal Antibody (RM192), ChIP-Verified

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

H3.3 K27M oncohistone mutant Recombinant Rabbit Monoclonal Antibody (RM192), ChIP-Verified

catalog :

MA5-27916

quantity :

100 uL

price :

US 530.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

RM192

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

citations: 2

Reference
van Ineveld R, Collot R, Rom xe1 n M, Pagliaro A, Bessler N, Ariese H, et al. Multispectral confocal 3D imaging of intact healthy and tumor tissue using mLSR-3D. Nat Protoc. 2022;17:3028-3055 pubmed publisher
Leske H, Dalgleish R, Lazar A, Reifenberger G, Cree I. A common classification framework for histone sequence alterations in tumours: an expert consensus proposal. J Pathol. 2021;254:109-120 pubmed publisher

product information

Product Type :

Antibody

Product Name :

H3.3 K27M oncohistone mutant Recombinant Rabbit Monoclonal Antibody (RM192), ChIP-Verified

Catalog # :

MA5-27916

Quantity :

100 uL

Price :

US 530.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

ChIP Assay: 1-5 ug, ELISA: 1:250-1:2,500, Immunocytochemistry: 1:100-1:500, Immunohistochemistry: 1:100-1:500, Western Blot: 1:250-1:2500

Species :

Human

Clone :

RM192

Isotype :

IgG

Storage :

-20 C

Description :

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Immunogen :

A peptide corresponding to Histone H3 K27M mutant

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 1-5 ug, ELISA: 1:250-1:2,500, Immunocytochemistry: 1:100-1:500, Immunohistochemistry: 1:100-1:500, Western Blot: 1:250-1:2500

Aliases :

H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K27; H3 K27M; H3.2; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-3A; H3-3B; H3a; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3F1K; H3F2; H3F3; H3F3A; H3F3B; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3K27 mutant; H3K27M; HIST1H3A; HIST1H3B; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST2H3A; HIST2H3C; HIST2H3D; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; Histone 3; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 2, H3a; histone cluster 2, H3c; Histone H3; Histone H3 K27M; histone H3.1; Histone H3.2; histone H3.3; Histone H3.3C; histone H3.5; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; histone H3/l; Histone H3/m; histone H3/o; Histone H3K27M; histone variant H3.5; PP781