PD-L1 (CD274) Recombinant Rabbit Monoclonal Antibody (RM320) | Invitrogen MA5-27896 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PD-L1 (CD274) Recombinant Rabbit Monoclonal Antibody (RM320)

catalog :

MA5-27896

quantity :

100 uL

price :

US 474.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

RM320

The same clone is also sold as:

Bio-Rad: MCA6329

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Yang F, Zeng Z, Li Y, Zhang D, Wei F, Zhao H, et al. The prognostic value of a 4-factor neoimmunologic score system in non-small cell lung cancer. J Leukoc Biol. 2022;112:1605-1619 pubmed publisher
Tokuyama M, Xu C, Fisher R, Wilson Rawls J, Kusumi K, Newbern J. Developmental and adult-specific processes contribute to de novo neuromuscular regeneration in the lizard tail. Dev Biol. 2018;433:287-296 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PD-L1 (CD274) Recombinant Rabbit Monoclonal Antibody (RM320)

Catalog # :

MA5-27896

Quantity :

100 uL

Price :

US 474.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:200-1:500, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:1,000

Species :

Human

Clone :

RM320

Isotype :

IgG

Storage :

-20 C

Description :

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.

Immunogen :

A peptide corresponding to the C-terminus of human PD-L1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:200-1:500, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:1,000

Aliases :

A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1