FIS1 Monoclonal Antibody (GT4211) | Invitrogen MA5-27835 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FIS1 Monoclonal Antibody (GT4211)

catalog :

MA5-27835

quantity :

100 uL

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GT4211

reactivity :

human

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

FIS1 Monoclonal Antibody (GT4211)

Catalog # :

MA5-27835

Quantity :

100 uL

Price :

US 484.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human

Clone :

GT4211

Isotype :

IgG2b

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Fis1, a 17KDa integral membrane protein, is a novel member of mitochondrial fission machinery. It consists of a central leucine-zipper domain, a coiled-coil region, a tetratricopeptide repeat domain and a C-terminal transmembrane domain. It is a human orthologue of Fis1p (S.cerevisiae) and is localized in the outer mitochondrial membrane. Fis1 acts as a pro-apoptotic factor and plays a vital role in the regulation of mitochondrial fission. It interacts with DLP1 and Mdv1p and facilitates Dnm1p recruitment to the functional fission complex, thereby inducing apoptosis. Role of Fis1 has also been implicated in growth and division of peroxisomes. Loss of Fis1 inhibits apoptosis and results in elongation of mammalian mitochondria.

Immunogen :

Full length human FIS1 Recombinant protein.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

2010003O14Rik; CGI-135; Fis1; fis1 {ECO:0000250; FIS1 homolog; fission 1 (mitochondrial outer membrane) homolog; fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); fission 1 (mitochondrial outer membrane) homolog (yeast); fission, mitochondrial 1; H_NH0132A01.6; hFis1; Mitochondrial fission 1 protein; mitochondrial fission molecule; rFis1; tetratricopeptide repeat domain 11; tetratricopeptide repeat protein 11; TPR repeat protein 11; TTC11; UniProtKB:Q9Y3D6}