BABAM1 Monoclonal Antibody (GT1251) | Invitrogen MA5-27830 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BABAM1 Monoclonal Antibody (GT1251)

catalog :

MA5-27830

quantity :

100 uL

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GT1251

reactivity :

human

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

BABAM1 Monoclonal Antibody (GT1251)

Catalog # :

MA5-27830

Quantity :

100 uL

Price :

US 484.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human

Clone :

GT1251

Isotype :

IgG2a

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

HSPC142 is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. HSPC142 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36.

Immunogen :

Recombinant protein encompassing a sequence within the N-terminus region of human C19orf62. The exact sequence is proprietary.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

5430437P03Rik; BABAM1; BRCA1-A complex subunit MERIT40; BRISC and BRCA1 A complex member 1; BRISC and BRCA1-A complex member 1; C19orf62; HSPC142; mediator of Rap80 interactions and targeting 40 kDa; mediator of RAP80 interactions and targeting subunit of 40 kDa; MERIT40; NBA1; new component of the BRCA1 A complex; new component of the BRCA1-A complex; new component of the BRCAA1 A complex