This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CaV1.2 Monoclonal Antibody (S57)
catalog :
MA5-27717
quantity :
100 ug
price :
US 504.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S57

The same clone is also sold as:
reactivity :
Chinese hamsters, human, mouse, rat, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 2
Reference
Lee B, Lee U, Ryu S, Han S, Lee S, Lee J, et al. L-type Ca2+ channels mediate regulation of glutamate release by subthreshold potential changes. Proc Natl Acad Sci U S A. 2023;120:e2220649120 pubmed publisher
J xe4 nsch M, Lubomirov L, Trum M, Williams T, Schmitt J, Schuh K, et al. Inducible over-expression of cardiac Nos1ap causes short QT syndrome in transgenic mice. FEBS Open Bio. 2023;13:118-132 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CaV1.2 Monoclonal Antibody (S57)
Catalog # :
MA5-27717
Quantity :
100 ug
Price :
US 504.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Hamster, Human, Mouse, Rabbit, Rat
Applications :
Antibody Microarray: Assay-dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:1,000, Immunoprecipitation: 1:200, Western Blot: 1:1,000
Species :
Hamster, Human, Mouse, Rabbit, Rat
Clone :
S57
Isotype :
IgG1
Storage :
-20 C
Description :
CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.
Immunogen :
Fusion protein amino acids 1507-1733 (intracellular carboxyl terminus) of rabbit Cav1.2
Format :
Liquid
Applications w/Dilutions :
Antibody Microarray: Assay-dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:1,000, Immunoprecipitation: 1:200, Western Blot: 1:1,000
Aliases :
brain class C; CACB; CaCB receptor; CACB-receptor; CACH2; CACH2C; CACH3; Cacn2; CACN4; CACNA 1D; Cacna1c; CACNL1A1; CACNL1A2; calcium channel; calcium channel voltage-dependent alpha1c subunit; calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit; calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle; calcium channel, voltage-dependent, alpha 1C subunit; calcium channel, voltage-dependent, L type, alpha 1C subunit; calcium voltage-gated channel subunit alpha1 C; cardiac L-type calcium channel; Cav1.2; CCHL1A1; D930026N18Rik; DHP receptor; DHPR, alpha-1 subunit; I79_006562; long-NT; LQT8; LTCC; L-type calcium channel alpha-1 subunit; MBC; MELC-CC; MGC120730; Mouse brain class C; neuronal voltage-gated calcium channel alpha 1C subunit; Rat brain class C; RATIVS302; RBC; skeletal muscle-specific calcium channel; smooth muscle calcium channel blocker; Smooth muscle calcium channel blocker receptor; TS; unnamed protein product; voltage-dependent L-type Ca2+ channel alpha 1 subunit; Voltage-dependent L-type calcium channel subunit alpha-1C; Voltage-gated calcium channel subunit alpha Cav1.2; voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA