Kir2.1 (KCNJ2) Monoclonal Antibody (S112) | Invitrogen MA5-27681 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Kir2.1 (KCNJ2) Monoclonal Antibody (S112)

catalog :

MA5-27681

quantity :

100 ug

price :

US 504.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S112

The same clone is also sold as:

Novus Biologicals: NBP2-12900
StressMarq Biosciences: SMC-310

reactivity :

human, mouse, rat, rhesus macaque

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Ivanova A, Filatova T, Abramochkin D, Atkinson A, Dobrzynski H, Kokaeva Z, et al. Attenuation of inward rectifier potassium current contributes to the α1-adrenergic receptor-induced proarrhythmicity in the caval vein myocardium. Acta Physiol (Oxf). 2021;231:e13597 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Kir2.1 (KCNJ2) Monoclonal Antibody (S112)

Catalog # :

MA5-27681

Quantity :

100 ug

Price :

US 504.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat, Rhesus Monkey

Applications :

Antibody Microarray: Assay-dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:1,000

Species :

Human, Mouse, Rat, Rhesus Monkey

Clone :

S112

Isotype :

IgG1

Storage :

-20 C

Description :

The KIR2 subunit family includes 2. 1, 2. 2, 2. 3 and 2. 4. Unlike G protein-coupled KIR3 subunits, KIR2. 1 requires both phosphorylation by PKA and ATP hydrolysis for functional activity. KIR2. 1 is expressed in the superior and inferior collicula and the pontine region of the brain, where it moderates synaptic transmission, like many other potassium channels. In the placenta, KIR2. 1 is expressed throughout gestation in cytotrophoblast cells. In the kidney, KIR2. 1 colocalizes with KIR5. 1 in the proximal tubule. KIR2. 1, 2. 2 and 2. 3 associate with the membrane-associated guanylate kinase synapseassociated protein 97 in the cerebellum and heart. Phosphorylation of KIR2. 2 by protein kinase A inhibits the associates with SAP97.

Immunogen :

Fusion protein amino acids 41-64 and 189-428 of mouse Kir2.1

Format :

Liquid

Applications w/Dilutions :

Antibody Microarray: Assay-dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:1,000

Aliases :

ATFB9; cardiac inward rectifier KIR2.1; cardiac inward rectifier potassium channel; EGK_08925; HHBIRK1; HHIRK 1; HHIRK1; HIRK 1; hIRK1; Inward rectifier K; inward rectifier K(+) channel Kir2.1; inward rectifier K+ channel KIR2.1; inward rectifier potassium channel; inward rectifier potassium channel 2; inwardly rectifying potassium channel Kir2.1; IRK 1; IRK1; IRK-1; IRK2; Kcnf1; KCNJ2; KIR2.1; LQT 7; LQT7; Potassium channel, inwardly rectifying subfamily J member 2; potassium channel, inwardly rectifying subfamily J, member 2; potassium inwardly rectifying channel subfamily J member 2; potassium inwardly-rectifying channel, subfamily J, member 2; potassium voltage-gated channel subfamily J member 2; RBL-IRK1; SQT 3; SQT3