This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
4-Hydroxynonenal Monoclonal Antibody (12F7)
catalog :
MA5-27570
quantity :
100 ug
price :
US 504.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
12F7
application :
western blot, ELISA, immunocytochemistry
citations: 17
Reference
Gale J, Hartnett Scott K, Ross M, Rosenberg P, Aizenman E. Copper induces neuron-sparing, ferredoxin 1-independent astrocyte toxicity mediated by oxidative stress. J Neurochem. 2023;167:277-295 pubmed publisher
Li Q, Du Y, Xiang P, Chen G, Qian X, Li S, et al. Re-Visiting Antioxidant Therapy in Murine Advanced Atherosclerosis with Brussels Chicory, a Typical Vegetable in Mediterranean Diets. Nutrients. 2023;15: pubmed publisher
Hosseini A, Stojkov D, Fettrelet T, Bilyy R, Yousefi S, Simon H. Transcriptional Insights of Oxidative Stress and Extracellular Traps in Lung Tissues of Fatal COVID-19 Cases. Int J Mol Sci. 2023;24: pubmed publisher
Hammers D. NOX4 inhibition promotes the remodeling of dystrophic muscle. JCI Insight. 2022;7: pubmed publisher
Torcinaro A, Cappetta D, De Santa F, Telesca M, Leigheb M, Berrino L, et al. Ranolazine Counteracts Strength Impairment and Oxidative Stress in Aged Sarcopenic Mice. Metabolites. 2022;12: pubmed publisher
Hossain M, Toltin A, Gamba L, Molina M. Deltamethrin-Evoked ER Stress Promotes Neuroinflammation in the Adult Mouse Hippocampus. Cells. 2022;11: pubmed publisher
Yang M, Tsui M, Tsang J, Goit R, Yao K, So K, et al. Involvement of FSP1-CoQ10-NADH and GSH-GPx-4 pathways in retinal pigment epithelium ferroptosis. Cell Death Dis. 2022;13:468 pubmed publisher
Zhang S, Hu L, Han C, Huang R, Ooi K, Qian X, et al. PLIN2 Mediates Neuroinflammation and Oxidative/Nitrosative Stress via Downregulating Phosphatidylethanolamine in the Rostral Ventrolateral Medulla of Stressed Hypertensive Rats. J Inflamm Res. 2021;14:6331-6348 pubmed publisher
You J, Lee J, Roh J. PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells. J Exp Clin Cancer Res. 2021;40:350 pubmed publisher
Wu W, Sun X, Shi X, Lai L, Wang C, Xie M, et al. Hsp22 Deficiency Induces Age-Dependent Cardiac Dilation and Dysfunction by Impairing Autophagy, Metabolism, and Oxidative Response. Antioxidants (Basel). 2021;10: pubmed publisher
Luo Q, Xian P, Wang T, Wu S, Sun T, Wang W, et al. Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage. Theranostics. 2021;11:5986-6005 pubmed publisher
Swiader A, Camaré C, Guerby P, Salvayre R, Negre Salvayre A. 4-Hydroxynonenal Contributes to Fibroblast Senescence in Skin Photoaging Evoked by UV-A Radiation. Antioxidants (Basel). 2021;10: pubmed publisher
Nesbitt N, Malone L, Liu Z, Jares A, Gnatenko D, Ma Y, et al. Divergent erythroid megakaryocyte fates in Blvrb-deficient mice establish non-overlapping cytoprotective functions during stress hematopoiesis. Free Radic Biol Med. 2021;164:164-174 pubmed publisher
Hu J, Pauer G, Hagstrom S, Bok D, DeBenedictis M, Bonilha V, et al. Evidence of complement dysregulation in outer retina of Stargardt disease donor eyes. Redox Biol. 2020;37:101787 pubmed publisher
Pushpakumar S, Ren L, Juin S, Majumder S, Kulkarni R, Sen U. Methylation-dependent antioxidant-redox imbalance regulates hypertensive kidney injury in aging. Redox Biol. 2020;37:101754 pubmed publisher
Lee J, You J, Kim M, Roh J. Epigenetic reprogramming of epithelial-mesenchymal transition promotes ferroptosis of head and neck cancer. Redox Biol. 2020;37:101697 pubmed publisher
Kalpage H, Wan J, Morse P, Lee I, Huttemann M. Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling. Cells. 2020;9: pubmed publisher
product information
Product Type :
Antibody
Product Name :
4-Hydroxynonenal Monoclonal Antibody (12F7)
Catalog # :
MA5-27570
Quantity :
100 ug
Price :
US 504.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Chemical
Applications :
ELISA: 1:1,000, Immunocytochemistry: 1:50, Western Blot: 1:1,000
Species :
Chemical
Clone :
12F7
Isotype :
IgG1
Storage :
-20 C
Description :
4-Hydroxynonenal, or 4-hydroxy-2-nonenal or 4-HNE or HNE, is an alpha, beta-unsaturated hydroxyalkenal that is produced by lipid peroxidation in cells. 4-HNE is the primary alpha, beta-unsaturated hydroxyalkenal formed in this process.
Immunogen :
Synthetic 4-Hydroxynonenal modified Keyhole Limpet Hemocyanin (KLH)
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:1,000, Immunocytochemistry: 1:50, Western Blot: 1:1,000
Aliases :
4HNE; 4-HNE; 4-hydroxy Hexenal; 4-Hydroxy Nonenal; 4-hydroxy-2-nonenal; 4-Hydroxynonenal; HNE
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA