HDEL Monoclonal Antibody (2E7) | Invitrogen MA5-27549 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HDEL Monoclonal Antibody (2E7)

catalog :

MA5-27549

quantity :

100 ug

price :

US 504.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2.00E+07

reactivity :

fruit fly

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

HDEL Monoclonal Antibody (2E7)

Catalog # :

MA5-27549

Quantity :

100 ug

Price :

US 504.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Drosophila, Plant, Yeast

Applications :

Immunocytochemistry: 1:100, Western Blot: 1:1,000

Species :

Drosophila, Plant, Yeast

Clone :

2.00E+07

Isotype :

IgG2b

Storage :

-20 C

Description :

HSP 70 family comprises four highly conserved proteins, HSP 70, HSC 70, GRP 75 and GRP 78, which serve a variety of roles. They act as molecular chaperones, facilitating the assembly of multi-protein complexes; participate in the translocation of polypeptides across cell membranes and to the nucleus; and aid in the proper folding of nascent polypeptide chains. GRP 78 is localized in the endoplasmic reticulum (ER), where it receives imported secretory proteins and is involved in the folding and translocation of nascent peptide chains. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually KDEL in animal cells, and HDEL in S.cerevisiae. The 2E7 clone recognizes the C-terminal peptide HDEL, a common version of the endoplasmic reticulum retention signal found in yeast, plant, nematode and other ER proteins. 2E7 specifically stains HDEL proteins in barnyard grass, beet, cotton, mung bean, sorghum and wheat.

Immunogen :

Raised against a synthetic HDEL peptide corresponding to the C-terminus of yeast Bip

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Western Blot: 1:1,000

Aliases :

BEST:CK00230; CG5183; CG5183-PA; CG5183-PB; CG5183-PC; CK00230; Dmel CG5183; Dmel_CG5183; dmErd2; ER lumem protein retaining receptor 2; ER lumen protein retaining receptor; ER lumen protein retaining receptor 2; ER lumen protein-retaining receptor; Erd2; KDEL receptor; KdelR; KDELR1; KDEL-receptor; KdelR-PA; KdelR-PB; KdelR-PC; l(2)31Em; l(2)k00311; lethal (2) 31Em