SCD Monoclonal Antibody (CD.E10) | Invitrogen MA5-27542 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SCD Monoclonal Antibody (CD.E10)

catalog :

MA5-27542

quantity :

100 ug

price :

US 524.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CD.E10

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; loading ...; fig 4	Korbecki J, Kojder K, Jezewski D, Simińska D, Tarnowski M, Kopytko P, et al. Expression of SCD and FADS2 Is Lower in the Necrotic Core and Growing Tumor Area than in the Peritumoral Area of Glioblastoma Multiforme. Biomolecules. 2020;10: pubmed publisher
	Mir S, Wong S, Narasimhan K, Esther C, Ji S, Burla B, et al. Lipidomic Analysis of Archival Pathology Specimens Identifies Altered Lipid Signatures in Ovarian Clear Cell Carcinoma. Metabolites. 2021;11: pubmed publisher
	Nicholatos J, Groot J, Dhokai S, Tran D, Hrdlicka L, Carlile T, et al. SCD Inhibition Protects from α-Synuclein-Induced Neurotoxicity But Is Toxic to Early Neuron Cultures. Eneuro. 2021;8: pubmed publisher

product information

Product Type :

Antibody

Product Name :

SCD Monoclonal Antibody (CD.E10)

Catalog # :

MA5-27542

Quantity :

100 ug

Price :

US 524.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: Assay-Dependent, Immunocytochemistry: 1:100-1:1,000, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Clone :

CD.E10

Isotype :

IgG2b

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5., have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates.

Immunogen :

Full length human recombinant protein against SCD1.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Immunocytochemistry: 1:100-1:1,000, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000

Aliases :

AA589638; ab; acyl-CoA desaturase; Acyl-CoA desaturase 1; acyl-CoA desaturase 2; AI265570; asebia; delta(9)-desaturase; Delta(9)-desaturase 1; delta(9)-desaturase 2; Delta-9 desaturase; delta-9 desaturase 1; Delta-9 desaturase 2; delta-9-desaturase; FADS5; fatty acid desaturase; Fatty acid desaturase 1; fatty acid desaturase 2; HGNC:10571; hSCD1; MSTP008; OTTHUMP00000020280; predicted protein of HQ0998; PRO0998; PRO1933; Scd; Scd1; Scd-1; Scd2; SCDOS; stearoyl-CoA desaturase; stearoyl-CoA desaturase (delta-9-desaturase); stearoyl-CoA desaturase 1; Stearoyl-CoA desaturase 2; stearoyl-CoA desaturase opposite strand; stearoyl-Coenzyme A desaturase 1; stearoyl-Coenzyme A desaturase 2; stearyl-CoA desaturase

more info or order :

Invitrogen product webpage