ADAMTS4 Monoclonal Antibody (OTI6F8) | Invitrogen MA5-26715 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ADAMTS4 Monoclonal Antibody (OTI6F8)

catalog :

MA5-26715

quantity :

100 uL

price :

US 510.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI6F8

The same clone is also sold as:

OriGene: TA805208, CF805208, TA805208BM, TA805208AM, TA805208S

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
He C, Clark K, Tan J, Zhou H, Tuan R, Lin H, et al. Modeling early changes associated with cartilage trauma using human-cell-laden hydrogel cartilage models. Stem Cell Res Ther. 2022;13:400 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ADAMTS4 Monoclonal Antibody (OTI6F8)

Catalog # :

MA5-26715

Quantity :

100 uL

Price :

US 510.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2,000

Species :

Human

Clone :

OTI6F8

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene encodes a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.

Immunogen :

Human recombinant protein fragment corresponding to amino acids 296-577 of ADAMTS4 produced in E.coli

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2,000

Aliases :

3830423K05; a disintegrin and metallopeptidase with thrombospondin motifs 4; a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 4; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 4; ADAM metallopeptidase with thrombospondin type 1 motif, 4; ADAMs; ADAM-TS 4; ADAMTS family member; ADAMTS-2; Adamts4; ADAM-TS4; ADAMTS-4; ADMP-1; Aggrecanase; Aggrecanase 1; aggrecanase-1; disintegrin and metalloproteinase with thrombospondin motifs 2; KIAA0688; metalloendopeptidases; metalloproteinase; mKIAA0688; UNQ769/PRO1563