LPIN3 Monoclonal Antibody (OTI1D7) | Invitrogen MA5-26707 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LPIN3 Monoclonal Antibody (OTI1D7)

catalog :

MA5-26707

quantity :

100 uL

price :

US 504.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI1D7

The same clone is also sold as:

OriGene: CF804944, TA804944AM, TA804944S, TA804944, TA804944BM

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

LPIN3 Monoclonal Antibody (OTI1D7)

Catalog # :

MA5-26707

Quantity :

100 uL

Price :

US 504.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500

Species :

Human

Clone :

OTI1D7

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice carrying mutations in the fatty liver dystrophy gene have similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches, mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes and three human homologs. Human LPIN1 gene has been mapped to 2p25.; linkages of fat mass and serum leptin levels to this same region have been noted. Human LPIN2 and LPIN3 mapped to chromosomes 18p11 and 20q11-q12, respectively. The mouse genes encoding Lpin1, Lpin2, and Lpin3 mapped to chromosome 12, 17, and 2, respectively.

Immunogen :

Full length human recombinant protein of LPIN3 produced in HEK293T cell

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500

Aliases :

9130206L11Rik; AA438110; AV236139; dJ450M14.2; dJ450M14.3; dJ620E11.2; lipin 3; lipin 3-like; lipin-3; Lipin-3-like; LIPN3L; Lpin3; mKIAA4023; Phosphatidate phosphatase LPIN3; RP4-620E11.3; SMP2