OAS2 Monoclonal Antibody (OTI6E6) | Invitrogen MA5-26552 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

OAS2 Monoclonal Antibody (OTI6E6)

catalog :

MA5-26552

quantity :

100 uL

price :

US 514.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI6E6

The same clone is also sold as:

OriGene: TA802772, CF802772, TA802772BM, TA802772AM, TA802772S

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Torices S, Téglás T, Naranjo O, Fattakhov N, Frydlova K, Cabrera R, et al. Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family. Mol Neurobiol. 2023;60:4966-4982 pubmed publisher

product information

Product Type :

Antibody

Product Name :

OAS2 Monoclonal Antibody (OTI6E6)

Catalog # :

MA5-26552

Quantity :

100 uL

Price :

US 514.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2,000

Species :

Human

Clone :

OTI6E6

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Immunogen :

Human recombinant protein fragment corresponding to amino acids 60-335 of OAS2 produced in E.coli

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2,000

Aliases :

(2-5')oligo(A) synthase 2; (2'-5')oligo(A) synthetase 2; 2',5'-oligoadenylate synthetase-like 11; 2,5-oligoadenylate synthetase-like 11; 2'-5' oligoadenylate synthetase 2; 2'-5' oligoadenylate synthetase-like 11; 2-5A synthase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; A synthetase 2; MGC78578; Oas2; Oasl11; p69 OAS / p71 OAS; p69OAS / p71OAS