This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PARN Monoclonal Antibody (OTI1G5)
catalog :
MA5-26543
quantity :
100 uL
price :
US 514.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
PARN Monoclonal Antibody (OTI1G5)
Catalog # :
MA5-26543
Quantity :
100 uL
Price :
US 514.00
Clonality :
Monoclonal
Purity :
Affinity Chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2,000
Species :
Human
Clone :
OTI1G5
Isotype :
IgG2a
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen :
Human recombinant protein fragment corresponding to amino acids 1-266 of PARN produced in E.coli
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2,000
Aliases :
1200003I18Rik; DAN; Deadenylating nuclease; deadenylation nuclease; DKCB6; Parn; PFBMFT4; poly(A)-specific ribonuclease; poly(A)-specific ribonuclease (deadenylation nuclease); poly(A)-specific ribonuclease PARN; Polyadenylate-specific ribonuclease; RGD1565449
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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