FAIM3 Monoclonal Antibody (OTI1E6) | Invitrogen MA5-26353 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FAIM3 Monoclonal Antibody (OTI1E6)

catalog :

MA5-26353

quantity :

100 uL

price :

US 514.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI1E6

The same clone is also sold as:

OriGene: TA507395, TA507395S, TA507395BM, TA507395AM

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Riba M, Campo Sabariz J, Tena I, Molina Porcel L, Ximelis T, Calvo M, et al. Wasteosomes (corpora amylacea) of human brain can be phagocytosed and digested by macrophages. Cell Biosci. 2022;12:177 pubmed publisher

product information

Product Type :

Antibody

Product Name :

FAIM3 Monoclonal Antibody (OTI1E6)

Catalog # :

MA5-26353

Quantity :

100 uL

Price :

US 514.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:150

Species :

Human

Clone :

OTI1E6

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Apoptosis is an important process by which normal tissue homeostasis and function are maintained. One of the major signals that regulate this process is mediated by the activation of the Fas receptor by its ligand. This leads to the formation of a Fas-associated death domain (FADD)- containing death-inducing signaling complex and the activation of caspase-8, which in turn activates downstream effector caspases, such as caspase-3 and -7. Recent experiments have shown that overexpression of Toso, a novel regulator of Fas-induced apoptosis in lymphoid cells, in Jurkat cells as well as transgenic mice render these cells resistant to Fas-induced apoptosis but not to TRAIL-induced apoptosis. Furthermore, Toso was found to associate with FADD, suggesting that Toso functions by disrupting the formation of the death-inducing signaling complex.

Immunogen :

Full length human recombinant protein of FAIM3 produced in HEK293 Cells.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:150

Aliases :

1810037B05Rik; Faim3; Fas apoptotic inhibitory molecule 3; Fc fragment of IgM receptor; Fc mu receptor; FCMR; FcmuR; IgM Fc fragment receptor; IgM Fc receptor; immunoglobulin mu Fc receptor; regulator of Fas-induced apoptosis Toso; TOSO