PIK3CG Monoclonal Antibody (OTI6H5) | Invitrogen MA5-26087 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PIK3CG Monoclonal Antibody (OTI6H5)

catalog :

MA5-26087

quantity :

100 uL

price :

US 504.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI6H5

The same clone is also sold as:

OriGene: CF505228, TA505228, TA505228S, TA505228BM, TA505228AM

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Taylor E, Byrum S, Edmondson J, Wardell C, Griffin B, Shalin S, et al. Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression. Acta Neuropathol Commun. 2020;8:157 pubmed publisher
Veselá B, Svandová E, Ramesova A, Kratochvilova A, Tucker A, Matalova E. Caspase Inhibition Affects the Expression of Autophagy-Related Molecules in Chondrocytes. Cartilage. 2021;13:956S-968S pubmed publisher

product information

Product Type :

Antibody

Product Name :

PIK3CG Monoclonal Antibody (OTI6H5)

Catalog # :

MA5-26087

Quantity :

100 uL

Price :

US 504.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Non-human primate

Applications :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:200-1:2,000

Species :

Human, Mouse, Non-human primate

Clone :

OTI6H5

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

PIK3CG (p110 gamma) is the sole class IB phosphatidylinositol 3-kinase family member, which along with the class IA family members, generates the important second messenger PIP2. However, unlike the class IA enzymes which signal downstream of receptor tyrosine kinases, PIK3CG primarily signals downstream of GPCRs. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.

Immunogen :

Full length human recombinant protein of PIK3CG produced in HEK293T cell

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:200-1:2,000

Aliases :

1-phosphatidylinositol 3-kinase; 5830428L06Rik; EGK_14026; p110gamma; p110-gamma; p120-PI3K; phosphatidylinositol 3 kinase gamma, p110 gamma; phosphatidylinositol 3-kinase catalytic 110-kD gamma; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Phosphoinositide-3-kinase catalytic gamma polypeptide; phosphoinositide-3-kinase gamma catalytic subunit; phosphoinositide-3-kinase, catalytic, gamma polypeptide; PI3CG; PI3K; pi3kcg; Pi3kg1; PI3Kgamma; PI3K-gamma; PI3-kinase subunit gamma; PIK3; Pik3cg; ptdIns-3-kinase subunit gamma; ptdIns-3-kinase subunit p110-gamma; Serine/threonine protein kinase PIK3CG