This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ACBD3 Monoclonal Antibody (OTI1G2)
catalog :
MA5-25989
quantity :
100 uL
price :
US 514.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI1G2

The same clone is also sold as:
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
ACBD3 Monoclonal Antibody (OTI1G2)
Catalog # :
MA5-25989
Quantity :
100 uL
Price :
US 514.00
Clonality :
Monoclonal
Purity :
Affinity Chromatography
Host :
Mouse
Reactivity :
Canine, Human, Mouse, Non-human primate, Rat
Applications :
Flow Cytometry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2,000
Species :
Canine, Human, Mouse, Non-human primate, Rat
Clone :
OTI1G2
Isotype :
IgG1
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure. GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160. GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event. GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.
Immunogen :
Full length human recombinant protein of ACBD3 produced in HEK293T cell
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2,000
Aliases :
60kDa; 8430407O11Rik; Acbd3; acyl-CoA binding domain containing 3; acyl-CoA-binding domain-containing protein 3; acyl-Coenzyme A binding domain containing 3; D1Ertd10e; DAP; DMT1-associated protein; fa20g08; GCP60; Gocap1; golgi complex associated protein 1, 60 kDa; golgi complex associated protein 1, 60kDa; golgi complex-associated protein 1; Golgi phosphoprotein 1; Golgi resident protein GCP60; Golgi resident protein GCP60, N-terminally processed; GOLPH1; neurotrophin receptor alike death domain protein; p75-like apoptosis-inducing death domain protein; Pap7; PBR- and PKA-associated protein 7; PBR associated protein; Peripheral benzodiazepine receptor-associated protein PAP7; peripherial benzodiazepine receptor associated protein; PKA (RIalpha)-associated protein; si:dkey-267p15.1; wu:fa20g08; zgc:66303
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA