NMT2 Monoclonal Antibody (OTI2A5) | Invitrogen MA5-25841 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NMT2 Monoclonal Antibody (OTI2A5)

catalog :

MA5-25841

quantity :

100 uL

price :

US 514.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI2A5

The same clone is also sold as:

OriGene: TA504177BM, TA504177S, TA504177AM, CF504177, TA504177

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Govatati S, Pichavaram P, Janjanam J, Guo L, Virmani R, Rao G. Myristoylation of LMCD1 Leads to Its Species-Specific Derepression of E2F1 and NFATc1 in the Modulation of CDC6 and IL-33 Expression During Development of Vascular Lesions. Arterioscler Thromb Vasc Biol. 2020;40:1256-1274 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NMT2 Monoclonal Antibody (OTI2A5)

Catalog # :

MA5-25841

Quantity :

100 uL

Price :

US 514.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat

Clone :

OTI2A5

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signaling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The 26S proteasome is an ATP-dependent, multisubunit (approximately 31), barrel-shaped molecular machine with an apparent molecular weight of approximately 2.5 MDa. It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes. The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit. An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation. Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway. Some examples of affected proteins include those linked to cystic fibrosis, Angelman's syndrome, and Liddle syndrome.

Immunogen :

Full length human recombinant protein of NMT2 produced in HEK293T cell

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2,000

Aliases :

A930001K02Rik; AI605445; AU044698; fb40e03; Glycylpeptide N-tetradecanoyltransferase 2; glycylpeptide N-tetradecanoyltransferase 2 variant 3; glycylpeptide N-tetradecanoyltransferase 2 variant 4; hNMT-2; myristoyl-CoA:protein N-myristoyltransferase 2; NMT 2; Nmt2; NMT2 protein; N-myristoyltransferase 2; peptide N-myristoyltransferase 2; Type II N-myristoyltransferase; wu:fb40e03