FDFT1 Monoclonal Antibody (OTI2F10) | Invitrogen MA5-25676 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FDFT1 Monoclonal Antibody (OTI2F10)

catalog :

MA5-25676

quantity :

100 uL

price :

US 504.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI2F10

The same clone is also sold as:

OriGene: CF503470, TA503470, TA503470BM, TA503470S, TA503470AM
Novus Biologicals: NBP2-01170, NBP2-70715

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Do T, Ma F, Andrade P, Teles R, de Andrade Silva B, Hu C, et al. TREM2 macrophages induced by human lipids drive inflammation in acne lesions. Sci Immunol. 2022;7:eabo2787 pubmed publisher

product information

Product Type :

Antibody

Product Name :

FDFT1 Monoclonal Antibody (OTI2F10)

Catalog # :

MA5-25676

Quantity :

100 uL

Price :

US 504.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:200-1:500

Species :

Human, Non-human primate

Clone :

OTI2F10

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.

Immunogen :

Full length human recombinant protein of FDFT1 produced in HEK293T cell

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:200-1:500

Aliases :

DGPT; EGK_18680; ERG9; farnesyl diphosphate farnesyl transferase 1; farnesyl diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase 1; FDFT1; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; Squalene synthase; squalene synthetase; SS