Aminoacylase Monoclonal Antibody (OTI2D3) | Invitrogen MA5-25618 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Aminoacylase Monoclonal Antibody (OTI2D3)

catalog :

MA5-25618

quantity :

100 uL

price :

US 514.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI2D3

The same clone is also sold as:

OriGene: TA503190AM, CF503190, TA503190BM, TA503190, TA503190S

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

Aminoacylase Monoclonal Antibody (OTI2D3)

Catalog # :

MA5-25618

Quantity :

100 uL

Price :

US 514.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Canine, Human, Mouse, Rat

Applications :

Flow Cytometry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:200-1:500

Species :

Canine, Human, Mouse, Rat

Clone :

OTI2D3

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

ACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21. 1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene. A related pseudogene has been identified on chromosome 18.

Immunogen :

Full length human recombinant protein of ACY1 produced in HEK293 cell

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:200-1:500

Aliases :

1110014J22Rik; ACY IA; ACY IB; ACY1; ACY-1; Acy1a; ACY-1A; Acy1b; ACY-1B; ACY1D; acylase; aminoacylase 1; aminoacylase I; aminoacylase-1; Aminoacylase-1A; aminoacylase-1B; epididymis secretory protein Li 5; HEL-S-5; N-acylamino acid aminohydrolase (Aminoacylase 1); N-acyl-L-amino-acid amidohydrolase