PRKAR1B Monoclonal Antibody (OTI9C5) | Invitrogen MA5-25526 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PRKAR1B Monoclonal Antibody (OTI9C5)

catalog :

MA5-25526

quantity :

100 uL

price :

US 514.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI9C5

The same clone is also sold as:

OriGene: CF502793, TA502793S, TA502793, TA502793AM, TA502793BM

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry

product information

Product Type :

Antibody

Product Name :

PRKAR1B Monoclonal Antibody (OTI9C5)

Catalog # :

MA5-25526

Quantity :

100 uL

Price :

US 514.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Western Blot: 1:2,000

Species :

Human, Mouse, Rat

Clone :

OTI9C5

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme resulting in release of active catalytic subunits. Three catalytic (C) subunits have been identified that each represent specific gene products. Activation of transcription upon elevation of cAMP levels results from translocation of PKA to the nucleus where it phosphorylates the transcrip- tion factor cAMP response element binding protein (CREB) on serine 133 which in turn leads to TFIIB binding to TATA-box-binding protein TBP1, thus linking phospho-CREB to the pol II transcription initiation complex.

Immunogen :

Full length human recombinant protein of PRKAR1B produced in HEK293T cell

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Western Blot: 1:2,000

Aliases :

AI385716; cAMP dependent protein kinase, subunit type 1 beta; cAMP dependent regulatory type I beta subunit transcript 2; cAMP dependent regulatory type I beta subunit transcript 3; cAMP dependent regulatory type I beta subunit transcript 4; cAMP-dependent protein kinase type I-beta regulatory subunit; PRKAR1; PRKAR1B; protein kinase cAMP-dependent type I regulatory subunit beta; protein kinase, cAMP dependent regulatory, type I beta; protein kinase, cAMP dependent regulatory, type I, beta; protein kinase, cAMP-dependent, regulatory subunit type I beta; protein kinase, cAMP-dependent, regulatory, type I, beta; RGD1563094; RIbeta