EXD1 Monoclonal Antibody (OTI2G5) | Invitrogen MA5-25350 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EXD1 Monoclonal Antibody (OTI2G5)

catalog :

MA5-25350

quantity :

100 uL

price :

US 514.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI2G5

The same clone is also sold as:

OriGene: TA502147AM, TA502147BM, CF502147, TA502147S, TA502147

reactivity :

human, rat

application :

western blot, flow cytometry

product information

Product Type :

Antibody

Product Name :

EXD1 Monoclonal Antibody (OTI2G5)

Catalog # :

MA5-25350

Quantity :

100 uL

Price :

US 514.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human, Non-human primate, Rat

Applications :

Flow Cytometry: 1:100, Western Blot: 1:200-1:500

Species :

Human, Non-human primate, Rat

Clone :

OTI2G5

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

EXD1 is an RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity. The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease.

Immunogen :

Full length human recombinant protein of EXD1 produced in HEK293T cell

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100, Western Blot: 1:200-1:500

Aliases :

4932702D22Rik; Exd1; EXDL1; exonuclease 3'-5' domain containing 1; exonuclease 3'-5' domain-containing protein 1; exonuclease 3'-5' domain-containing protein 1; piRNA biogenesis protein EXD1; exonuclease 3'-5' domain-like 1; exonuclease 3'-5' domain-like-containing protein 1; Inactive exonuclease EXD1; mExd1; piRNA biogenesis protein EXD1; RGD1561009; Vexonuclease 3'-5' domain-like 1