QPRT Monoclonal Antibody (OTI1C10) | Invitrogen MA5-25200 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

QPRT Monoclonal Antibody (OTI1C10)

catalog :

MA5-25200

quantity :

100 uL

price :

US 504.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI1C10

The same clone is also sold as:

Novus Biologicals: NBP2-73761, NBP2-02860
OriGene: TA501524S, TA501524BM, TA501524AM, TA501524, CF501524

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Jane E, Premkumar D, Thambireddy S, Golbourn B, Agnihotri S, Bertrand K, et al. Targeting NAD+ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance. Mol Cancer Res. 2020;18:1004-1017 pubmed publisher

product information

Product Type :

Antibody

Product Name :

QPRT Monoclonal Antibody (OTI1C10)

Catalog # :

MA5-25200

Quantity :

100 uL

Price :

US 504.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2,000

Species :

Human

Clone :

OTI1C10

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

QPRT gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.

Immunogen :

Full length human recombinant protein of QPRT produced in HEK293T cell

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2,000

Aliases :

2410027J01Rik; AI647766; epididymis secretory sperm binding protein Li 90n; HEL-S-90n; nicotinate-nucleotide pyrophosphorylase; nicotinate-nucleotide pyrophosphorylase (carboxylating); nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; QPRT; QPRTase; quinolinate phosphoribosyltransferase; Quinolinate phosphoribosyltransferase [decarboxylating]