This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
FADD Monoclonal Antibody (OTI1C11)
catalog :
MA5-25179
quantity :
100 uL
price :
US 504.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI1C11
The same clone is also sold as:
The same clone is also sold as:
- Abcam: ab119059
- OriGene: CF501434, TA501434, TA501434BM, TA501434S, TA501434AM
reactivity :
human
application :
western blot, flow cytometry
product information
Product Type :
Antibody
Product Name :
FADD Monoclonal Antibody (OTI1C11)
Catalog # :
MA5-25179
Quantity :
100 uL
Price :
US 504.00
Clonality :
Monoclonal
Purity :
Affinity Chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1:100, Western Blot: 1:2,000
Species :
Human
Clone :
OTI1C11
Isotype :
IgG1
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Immunogen :
Full length human recombinant protein of FADD produced in HEK293T cell
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100, Western Blot: 1:2,000
Aliases :
Fadd; Fas (TNFRSF6)-associated via death domain; Fas associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; Fas-associating protein with death domain; GIG3; Growth-inhibiting gene 3 protein; mediator of receptor induced toxicity; mediator of receptor-induced toxicity; MGC8528; MORT1; Mort1/FADD; protein FADD
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
questions and comments