This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
RNF144B Monoclonal Antibody (OTI11F4)
catalog :
MA5-24994
quantity :
100 uL
price :
US 514.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI11F4

The same clone is also sold as:
reactivity :
human
application :
western blot, immunocytochemistry, flow cytometry
product information
Product Type :
Antibody
Product Name :
RNF144B Monoclonal Antibody (OTI11F4)
Catalog # :
MA5-24994
Quantity :
100 uL
Price :
US 514.00
Clonality :
Monoclonal
Purity :
Affinity Chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Western Blot: 1:2,000
Species :
Human
Clone :
OTI11F4
Isotype :
IgG1
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.
Immunogen :
Human recombinant protein fragment corresponding to amino acids 1-256 of RNF144B produced in E. coli.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Western Blot: 1:2,000
Aliases :
bA528A10.3; BC025007; E130105P19Rik; E3 ubiquitin-protein ligase RNF144B; IBR domain containing 2; IBR domain-containing protein 2; IBRDC2; p53-inducible RING finger protein; p53RFP; PIR2; RING finger protein 144B; Rnf144b
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA