TRIB2 Monoclonal Antibody (OTI8D11) | Invitrogen MA5-24942 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRIB2 Monoclonal Antibody (OTI8D11)

catalog :

MA5-24942

quantity :

100 uL

price :

US 504.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI8D11

The same clone is also sold as:

OriGene: TA500510S, TA500510BM, TA500510AM, CF500510, TA500510
Novus Biologicals: NBP2-74597, NBP1-48030

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Wang J, Zuo J, Wahafu A, Wang M, Li R, Xie W. Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma. CNS Neurosci Ther. 2020;26:297-308 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TRIB2 Monoclonal Antibody (OTI8D11)

Catalog # :

MA5-24942

Quantity :

100 uL

Price :

US 504.00

Clonality :

Monoclonal

Purity :

Affinity Chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1:100, Immunocytochemistry: 1:50, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:1,000-1:2,000

Species :

Human

Clone :

OTI8D11

Isotype :

IgG2b

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Immunogen :

Full length human recombinant protein of TRIB2 produced in HEK293T cell

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100, Immunocytochemistry: 1:50, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:1,000-1:2,000

Aliases :

AW319517; C5FW; GS3955; RGD1564451; TRB2; TRB-2; trib2; TRIB2 (HGNC:30809); Tribbles homolog 2; tribbles homolog 2 (Drosophila); tribbles pseudokinase 2