5-Methylcytosine Recombinant Rabbit Monoclonal Antibody (RM231) | Invitrogen MA5-24694 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

5-Methylcytosine Recombinant Rabbit Monoclonal Antibody (RM231)

catalog :

MA5-24694

quantity :

50 ug

price :

US 414.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

RM231

application :

immunocytochemistry, immunoprecipitation, flow cytometry, dot blot

citations: 2

Reference
Cheng Y, Liu M, Hu M, Wang S. TAD-like single-cell domain structures exist on both active and inactive X chromosomes and persist under epigenetic perturbations. Genome Biol. 2021;22:309 pubmed publisher
Kalinka A, Achrem M. The distribution pattern of 5-methylcytosine in rye (Secale L.) chromosomes. PLoS ONE. 2020;15:e0240869 pubmed publisher

product information

Product Type :

Antibody

Product Name :

5-Methylcytosine Recombinant Rabbit Monoclonal Antibody (RM231)

Catalog # :

MA5-24694

Quantity :

50 ug

Price :

US 414.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Chemical

Applications :

Dot Blot: 0.5-2 ug/mL, ELISA: 0.1-3 ug/mL, Flow Cytometry: 0.5-2 ug/mL, Immunocytochemistry: 0.5-2 ug/mL, Immunoprecipitation: 0.2-2 ug/mL

Species :

Chemical

Clone :

RM231

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.

Immunogen :

BSA-conjugated 5-methylcytosine

Format :

Liquid

Applications w/Dilutions :

Dot Blot: 0.5-2 ug/mL, ELISA: 0.1-3 ug/mL, Flow Cytometry: 0.5-2 ug/mL, Immunocytochemistry: 0.5-2 ug/mL, Immunoprecipitation: 0.2-2 ug/mL

Aliases :

5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3