Histone H3.3 Recombinant Rabbit Monoclonal Antibody (RM190) | Invitrogen MA5-24667 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Histone H3.3 Recombinant Rabbit Monoclonal Antibody (RM190)

catalog :

MA5-24667

quantity :

100 ug

price :

US 434.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

RM190

reactivity :

human

application :

western blot, ELISA

citations: 2

Reference
Zhu J, Chen K, Sun Y, Ye W, Liu J, Zhang D, et al. LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei. Nat Commun. 2023;14:957 pubmed publisher
Bryant L, Li D, Cox S, Marchione D, Joiner E, Wilson K, et al. Histone H3.3 beyond cancer: Germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients. Sci Adv. 2020;6: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Histone H3.3 Recombinant Rabbit Monoclonal Antibody (RM190)

Catalog # :

MA5-24667

Quantity :

100 ug

Price :

US 434.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Non-human primate

Applications :

ChIP Assay: 1.5 ug/1x10^6 cells, ELISA: 0.2-1 ug/mL, Luminex: 0.05-0.5 ug/mL, Western Blot: 0.5-2 ug/mL

Species :

Human, Non-human primate

Clone :

RM190

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Immunogen :

Peptide corresponding to human Histone H3.3.

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 1.5 ug/1x10^6 cells, ELISA: 0.2-1 ug/mL, Luminex: 0.05-0.5 ug/mL, Western Blot: 0.5-2 ug/mL

Aliases :

9430068D06Rik; CG5825; CG5825-PA; CG5825-PC; CG5825-PD; CG8989; dH3.3A; Dmel CG5825; Dmel_CG5825; family 3B (H3.3B); H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3.3; H3.3 histone A; H3.3 histone B; H3.3A; H3.3A/B; H3.3B; H3.4; H3.A; H3.B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3A protein; H3F3B; H3FT; H3-IX; H3L-like histone; H3t; H3-X; His3.3; His3.3A; His-3.3A; His3.3A-PA; His3.3A-PC; His3.3A-PD; His3.3B; histone; Histone cluster 3; Histone H3; histone H3 class II; Histone H3.3; histone H3.3A; Histone H3.3B; histone H3.3-like protein; MGC126886; MGC126888; PH3; PP781; similar to H3 histone, family 3A; unnamed protein product