Norepinephrine Transporter Monoclonal Antibody (CL3063) | Invitrogen MA5-24647 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Norepinephrine Transporter Monoclonal Antibody (CL3063)

catalog :

MA5-24647

quantity :

100 uL

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CL3063

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:500; loading ...; fig 1a	Sakakibara Y, Hirota Y, Ibaraki K, Takei K, Chikamatsu S, Tsubokawa Y, et al. Widespread Reduced Density of Noradrenergic Locus Coeruleus Axons in the App Knock-In Mouse Model of Amyloid-β Amyloidosis. J Alzheimers Dis. 2021;82:1513-1530 pubmed publisher
	Pilski A, Graves S. Repeated Methamphetamine Administration Results in Axon Loss Prior to Somatic Loss of Substantia Nigra Pars Compacta and Locus Coeruleus Neurons in Male but Not Female Mice. Int J Mol Sci. 2023;24: pubmed publisher
	Du Y, Choi S, Pilski A, Graves S. Differential vulnerability of locus coeruleus and dorsal raphe neurons to chronic methamphetamine-induced degeneration. Front Cell Neurosci. 2022;16:949923 pubmed publisher
	Omoluabi T, Torraville S, Maziar A, Ghosh A, Power K, Reinhardt C, et al. Novelty-like activation of locus coeruleus protects against deleterious human pretangle tau effects while stress-inducing activation worsens its effects. Alzheimers Dement (N Y). 2021;7:e12231 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Norepinephrine Transporter Monoclonal Antibody (CL3063)

Catalog # :

MA5-24647

Quantity :

100 uL

Price :

US 480.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:200-1:500

Species :

Human, Mouse, Rat

Clone :

CL3063

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Norepinephrine Transporter [NET, or noradrenaline transporter (NAT)] is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression. Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD.

Immunogen :

Recombinant protein corresponding to Human Norepinephrine Transporter

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:200-1:500

Aliases :

NaCl-dependent norepinephrine transporter; NAT1; NE transporter; NET; NE-T; NET1; neurotransmitter transporter; neurotransmitter transporter, noradrenal; NORADR; noradrenaline; noradrenaline transporter; norepinephrine transporter; Slc6a2; SLC6A5; sodium-dependent noradrenaline transporter; solute carrier family 6 (neurotransmitter transporter), member 2; solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; solute carrier family 6 member 2; solute carrier family 6 member 5; transmembrane region 4. 26 transmembrane region 55. 77 transmembrane region 105. 123 transmembrane region 136. 157

more info or order :

Invitrogen product webpage