NSD2 Monoclonal Antibody (CL1063) | Invitrogen MA5-24621 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NSD2 Monoclonal Antibody (CL1063)

catalog :

MA5-24621

quantity :

100 uL

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CL1063

The same clone is also sold as:

Novus Biologicals: NBP2-52963

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Bao Z, Yao D, Qian X, Zhang H, Yang M, Guo Y, et al. Activating transcription factor 2 promotes the progression of hepatocellular carcinoma by inducing the activation of the WHSC1-mediated TOP2A/PI3K/AKT axis. Kaohsiung J Med Sci. 2022;38:662-674 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NSD2 Monoclonal Antibody (CL1063)

Catalog # :

MA5-24621

Quantity :

100 uL

Price :

US 480.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 2-10 ug/mL, Immunohistochemistry (Paraffin): 1:500-1:1,000, Western Blot: 1 ug/mL

Species :

Human

Clone :

CL1063

Isotype :

IgG2b

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Immunogen :

Recombinant protein corresponding to Human NSD2

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2-10 ug/mL, Immunohistochemistry (Paraffin): 1:500-1:1,000, Western Blot: 1 ug/mL

Aliases :

5830445G22Rik; 9430010A17Rik; AW555663; C130020C13Rik; D030027O06Rik; D930023B08Rik; Histone-lysine N-methyltransferase NSD2; histone-lysine N-methyltransferase NSD2; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase NSD2; IL5 promoter REII region-binding protein; Kiaa1090; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase NSD2; mKIAA1090; MMSET; multiple myeloma SET domain containing protein type III; multiple myeloma SET domain-containing protein; NSD2; nuclear receptor binding SET domain protein 2; nuclear SET domain-containing protein 2; probable histone-lysine N-methyltransferase NSD2; Protein trithorax-5; putative histone-lysine N-methyltransferase NSD2-like protein; REIIBP; RGD1565590; trithorax/ash1-related protein 5; TRX5; WHS; Whsc1; Whsc1l; Wolf-Hirschhorn syndrome candidate 1; Wolf-Hirschhorn syndrome candidate 1 (human); Wolf-Hirschhorn syndrome candidate 1 protein; Wolf-Hirschhorn syndrome candidate 1 protein homolog