Zika Virus NS1 Monoclonal Antibody (A831) | Invitrogen MA5-24584 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Zika Virus NS1 Monoclonal Antibody (A831)

catalog :

MA5-24584

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

A831

application :

immunocytochemistry

product information

Product Type :

Antibody

Product Name :

Zika Virus NS1 Monoclonal Antibody (A831)

Catalog # :

MA5-24584

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Virus

Applications :

ELISA: 1:20-1:200, Immunocytochemistry: 1:10-1:50

Species :

Virus

Clone :

A831

Isotype :

IgG1

Storage :

4 C

Description :

As a member of the Flaviviridae family, ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-transitionally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5)(1). The glycosated NS1 forms a homodimer inside the cells and is necessary for viral replication and late in infection (2). NS1 is also secreted into the extracellular space as a hexameric lipoprotein particle, which assists the virus in immune evasion and pathogenesis by interacting with components from both innate and adaptive immune systems as well as other host factors (1). Reference 1) Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F. (2016). Nat. Struct. Mol. Biol. 23, 456-458. 2) Suthar, M.S., Diamond, M.S. & Gale, M. Jr. (2013). Nat. Rev. Microbiol. 11, 115-128.

Immunogen :

recombinant Zika Virus NS1 protien

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:20-1:200, Immunocytochemistry: 1:10-1:50

Aliases :

Zika NS1; ZIKV NS1; ZIKV-NS1