DIO1 Monoclonal Antibody (1E4) | Invitrogen MA5-24403 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DIO1 Monoclonal Antibody (1E4)

catalog :

MA5-24403

quantity :

100 ug

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1.00E+04

reactivity :

human

product information

Product Type :

Antibody

Product Name :

DIO1 Monoclonal Antibody (1E4)

Catalog # :

MA5-24403

Quantity :

100 ug

Price :

US 474.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 10 ng/mL

Species :

Human

Clone :

1.00E+04

Isotype :

IgG2a, kappa

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The protein encoded by this gene is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD). Alternative splicing results in multiple transcript variants encoding different isoforms. Some, but not all, isoforms contain a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Additional transcript variants have been described but are not supported by experimental evidence.

Immunogen :

DIO1 (NP_000783.2, 35 a.a. ~ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Format :

Liquid

Applications w/Dilutions :

ELISA: 10 ng/mL

Aliases :

5DI; D1; deiodinase, iodothyronine type I; deiodinase, iodothyronine, type I; Dio1; DIOI; hDido1; iodothyronine deiodinase type 1; ITDI1; thyroxine 5'-deiodinase; thyroxine deiodinase; thyroxine deiodinase type I (selenoprotein); thyroxine deiodinase, type I; TXDI1; Type 1 DI; type I iodothyronine deiodinase; Type-I 5'-deiodinase