XRCC4 Monoclonal Antibody (5C10) | Invitrogen MA5-24383 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

XRCC4 Monoclonal Antibody (5C10)

catalog :

MA5-24383

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5c10

reactivity :

human, mouse

application :

western blot, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

XRCC4 Monoclonal Antibody (5C10)

Catalog # :

MA5-24383

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Antigen affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunoprecipitation: 1:200, Western Blot: 1:2,000

Species :

Human, Mouse

Clone :

5C10

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad51. XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination. Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation.

Immunogen :

Recombinant Protein of Human XRCC4

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: 1:200, Western Blot: 1:2,000

Aliases :

2310057B22Rik; AW413319; AW545101; DNA repair protein XRCC4; SSMED; X-ray repair complementing defective repair in Chinese hamster cells 4; X-ray repair cross complementing 4; X-ray repair cross complementing protein 4; X-ray repair cross-complementing protein 4; XRCC4