Thrombomodulin Monoclonal Antibody (461714) | Invitrogen MA5-24181 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Thrombomodulin Monoclonal Antibody (461714)

catalog :

MA5-24181

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

461714

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 3c	Welsh J, Hoofnagle M, Bamezai S, Oxendine M, Lim L, Hall J, et al. Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis. J Clin Invest. 2019;129:5489-5500 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Thrombomodulin Monoclonal Antibody (461714)

Catalog # :

MA5-24181

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 2.5 ug per million cells, Immunocytochemistry: 8-25 ug/mL, Immunohistochemistry (Frozen): 8-25 ug/mL, Western Blot: 1 ug/mL

Species :

Mouse

Clone :

461714

Isotype :

IgG2b

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.

Immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Thrombomodulin/BDCA-3 Leu17-Ser517

Format :

Lyophilized

Applications w/Dilutions :

Flow Cytometry: 2.5 ug per million cells, Immunocytochemistry: 8-25 ug/mL, Immunohistochemistry (Frozen): 8-25 ug/mL, Western Blot: 1 ug/mL

Aliases :

AHUS6; AI385582; BDCA3; BDCA-3; CD141; CD141 antigen; DC141; fetomodulin; sCD141; snoRNA MBII-339; soluble CD141; THBD; THPH12; THRM; thrombomdulin; thrombomodulin; thrombomodulin precursor; TM

more info or order :

Invitrogen product webpage