This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
C2 Monoclonal Antibody (269716)
catalog :
MA5-23970
quantity :
100 ug
price :
US 414.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
269716

The same clone is also sold as:
reactivity :
human
application :
western blot, immunoprecipitation
citations: 1
Reference
Spirig R, Campbell I, Koernig S, Chen C, Lewis B, BUTCHER R, et al. rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs. J Immunol. 2018;200:2542-2553 pubmed publisher
product information
Product Type :
Antibody
Product Name :
C2 Monoclonal Antibody (269716)
Catalog # :
MA5-23970
Quantity :
100 ug
Price :
US 414.00
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Human
Applications :
Immunoprecipitation: 25 ug/mL, Western Blot: 1 ug/mL
Species :
Human
Clone :
269716
Isotype :
IgG2a
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Component C2 is a serum glycoprotein that functions aspart of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
Immunogen :
Mouse myeloma cell line NS0-derived recombinant human Complement Component C2 Ala21-Leu752
Format :
Lyophilized
Applications w/Dilutions :
Immunoprecipitation: 25 ug/mL, Western Blot: 1 ug/mL
Aliases :
ARMD14; C2; C3/C5 convertase; classical-complement pathway C3/C5 convertase; CO2; Complement C2; Complement C2a fragment; Complement C2b fragment; complement component 2; complement component 2 (within H-2S); complement component C2; complement factor C2; DADB-122G4.1; I79_016440; MHC complement component C2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA