LRP6 Monoclonal Antibody (255302) | Invitrogen MA5-23950 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LRP6 Monoclonal Antibody (255302)

catalog :

MA5-23950

quantity :

100 ug

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

255302

The same clone is also sold as:

R&D Systems: FAB1505A, FAB1505P, MAB1505

reactivity :

human

application :

immunocytochemistry, flow cytometry

product information

Product Type :

Antibody

Product Name :

LRP6 Monoclonal Antibody (255302)

Catalog # :

MA5-23950

Quantity :

100 ug

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 2.5 ug per million cells, Immunocytochemistry: 8-25 ug/mL

Species :

Human

Clone :

255302

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.

Immunogen :

Mouse myeloma cell line NS0-derived recombinant human LRP-6 Ala20-Pro1368

Format :

Lyophilized

Applications w/Dilutions :

Flow Cytometry: 2.5 ug per million cells, Immunocytochemistry: 8-25 ug/mL

Aliases :

ADCAD2; C030016K15Rik; Cd; crooked; FLJ90062; FLJ90421; Gw; LDL receptor related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6; low density lipoprotein-related protein 6; low-density lipoprotein receptor-related protein 6; lpr6; LRP6; LRP-6; ska ; ska26; skax26; STHAG7