ULBP1 Monoclonal Antibody (237104) | Invitrogen MA5-23945 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ULBP1 Monoclonal Antibody (237104)

catalog :

MA5-23945

quantity :

100 ug

price :

US 450.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

237104

The same clone is also sold as:

R&D Systems: FAB2588P, FAB2588A, FAB2588N-100UG, MAB2588

reactivity :

mouse

application :

flow cytometry

citations: 1

Reference
Thompson T, Jackson B, Li P, Wang J, Kim A, Huang K, et al. Tumor-derived CSF-1 induces the NKG2D ligand RAE-1δ on tumor-infiltrating macrophages. elife. 2018;7: pubmed publisher

product information

Product Type :

Antibody

Product Name :

ULBP1 Monoclonal Antibody (237104)

Catalog # :

MA5-23945

Quantity :

100 ug

Price :

US 450.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 ug per million cells

Species :

Mouse

Clone :

237104

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

ULBP1 is the ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.

Immunogen :

BaF3 mouse pro-B cell line transfected with mouse ULBP-1/MULT-1

Format :

Lyophilized

Applications w/Dilutions :

Flow Cytometry: 0.25 ug per million cells

Aliases :

A430108B07Rik; ALCAN-beta; MULT1; N2DL1; N2DL-1; NKG2D ligand; NKG2D ligand 1; NKG2D ligand1; NKG2DL1; RAET1I; retinoic acid early transcript 1I; UL16 binding protein 1; UL16-binding protein 1; UL16-binding protein-like transcript 1; ULBP; ULBP 1; ULBP1