S100A12 Monoclonal Antibody (161205) | Invitrogen MA5-23925 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

S100A12 Monoclonal Antibody (161205)

catalog :

MA5-23925

quantity :

100 ug

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

161205

The same clone is also sold as:

R&D Systems: FAB10521P-100, MAB10521

reactivity :

human

application :

western blot, flow cytometry

product information

Product Type :

Antibody

Product Name :

S100A12 Monoclonal Antibody (161205)

Catalog # :

MA5-23925

Quantity :

100 ug

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 2.5 ug per million cells, Western Blot: 1 ug/mL

Species :

Human

Clone :

161205

Isotype :

IgG2b

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE. S100A12 has also been shown to have anti-microbial properties.

Immunogen :

E. coli-derived recombinant human EN-RAGE Met1-Glu92

Format :

Lyophilized

Applications w/Dilutions :

Flow Cytometry: 2.5 ug per million cells, Western Blot: 1 ug/mL

Aliases :

CAAF1; CAGC; Calcitermin; calcium-binding protein in amniotic fluid 1; calgranulin C; calgranulin-C; CGRP; EN RAGE; ENRAGE; EN-RAGE; Extracellular newly identified RAGE-binding protein; migration inhibitory factor-related protein 6; MRP6; MRP-6; Neutrophil S100 protein; p6; Protein S100 A12; protein S100-A12; S100 calcium binding protein A12; S100 calcium-binding protein A12; S100 calcium-binding protein A12 (calgranulin C); S100A12