CD357 (AITR/GITR) Monoclonal Antibody (110416) | Invitrogen MA5-23854 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD357 (AITR/GITR) Monoclonal Antibody (110416)

catalog :

MA5-23854

quantity :

100 ug

price :

US 440.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

110416

The same clone is also sold as:

R&D Systems: FAB689P-100, MAB689-100, FAB689A-100, FAB689N-100, FAB689F-100

reactivity :

human

application :

western blot, ELISA, neutralization, flow cytometry

product information

Product Type :

Antibody

Product Name :

CD357 (AITR/GITR) Monoclonal Antibody (110416)

Catalog # :

MA5-23854

Quantity :

100 ug

Price :

US 440.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 0.1-0.4 ug/mL (Detection), 2-8 ug/mL (Capture), Flow Cytometry: 2.5 ug per million cells, Neutralization: 1-2 ug/mL, Western Blot: 1 ug/mL

Species :

Human

Clone :

110416

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Immunogen :

Mouse myeloma cell line NS0-derived recombinant human GITR/TNFRSF18 Gln26-Glu161 (Thr43Ala)

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 0.1-0.4 ug/mL (Detection), 2-8 ug/mL (Capture), Flow Cytometry: 2.5 ug per million cells, Neutralization: 1-2 ug/mL, Western Blot: 1 ug/mL

Aliases :

Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364