EpoR Monoclonal Antibody (38409) | Invitrogen MA5-23824 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EpoR Monoclonal Antibody (38409)

catalog :

MA5-23824

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

38409

reactivity :

human

application :

western blot, immunoprecipitation, flow cytometry

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; fig 4f	Khalil S, Delehanty L, Grado S, Holy M, White Z, Freeman K, et al. Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor. J Exp Med. 2018;215:661-679 pubmed publisher
	LePage D, Metcalf J, Bordenstein S, On J, Perlmutter J, Shropshire J, et al. Prophage WO genes recapitulate and enhance Wolbachia-induced cytoplasmic incompatibility. Nature. 2017;543:243-247 pubmed publisher

product information

Product Type :

Antibody

Product Name :

EpoR Monoclonal Antibody (38409)

Catalog # :

MA5-23824

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 ug/10^6 cells, Immunoprecipitation: Assay-Dependent, Western Blot: 2 ug/mL

Species :

Human

Clone :

38409

Isotype :

IgG2b

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

EpoR encodes the erythropoietin receptor, which belongs to the cytokine receptor family. When erythropoietin binds to this receptor, it activates the Jak2 tyrosine kinase, which in turn activates various intracellular pathways including Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors. The stimulated erythropoietin receptor plays a role in the survival of erythroid cells. Defects in this gene may result in erythroleukemia and familial erythrocytosis. Dysregulation of this gene may also affect the growth of certain tumors. Multiple transcript variants are produced as a result of alternate splicing. Diseases associated with EPOR include Erythrocytosis, Familial, 1 and Erythroleukemia.

Immunogen :

Mouse myeloma cell line NS0-derived recombinant human Erythropoietin R Pro26-Pro250

Format :

Lyophilized

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/10^6 cells, Immunoprecipitation: Assay-Dependent, Western Blot: 2 ug/mL

Aliases :

EPO R; EPOR; EPO-R; Erythropoietin receptor; pEpoR

more info or order :

Invitrogen product webpage