TGF beta-3 Monoclonal Antibody (20724) | Invitrogen MA5-23812 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TGF beta-3 Monoclonal Antibody (20724)

catalog :

MA5-23812

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

20724

The same clone is also sold as:

R&D Systems: BAM243, MAB243-100

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, neutralization, immunohistochemistry - paraffin section

citations: 1

Reference
Bamford A, Hart M, Lyall H, Goldblatt D, Kelleher P, Kampmann B. The influence of paediatric HIV infection on circulating B cell subsets and CXCR5(+) T helper cells. Clin Exp Immunol. 2015;181:110-7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TGF beta-3 Monoclonal Antibody (20724)

Catalog # :

MA5-23812

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human, Many, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 8-25 ug/mL, Neutralization: 0.1-0.3 ug/mL, Western Blot: 1 ug/mL

Species :

Human, Many, Mouse, Rat

Clone :

20724

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Transforming growth factor beta 3 (TGF beta 3) is the third member of the transforming growth factor family of cytokines, which also includes TGF beta 1 and beta 2. These cytokines are secreted in precursor form consisting of a bioactive C-terminal domain attached to an N-terminal domain known as latency associated protein (LAP). Cleavage of LAP results in the mature protein, which functions as a disulfide-linked homodimer. As with all members of the family, TGF beta 3 is highly conserved across species, with mouse and human TGF beta 3 demonstrating 100% sequence homology and cross-species activity.The members of this family can be expressed by most cell types and exert pleiotropic effects, which include the suppression of B- and T-cell effector activity, mediation of tissue healing, and suppression of tumor proliferation. The promotion of CD4+CD25+ T-cell expansion is a newly discovered function of the TGF beta cytokines, and indicates an important role in the protection against autoimmunity.

Immunogen :

Sf 21-derived recombinant human TGF-beta 3 Ala301-Ser412 (Tyr340Phe)

Format :

Lyophilized

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 8-25 ug/mL, Neutralization: 0.1-0.3 ug/mL, Western Blot: 1 ug/mL

Aliases :

ARVD; ARVD1; FLJ16571; H-TGF-b-3; LAP; Latency-associated peptide; LDS5; prepro-transforming growth factor beta-3; RNHF; TGF beta 3; Tgfb3; TGF-B3; Tgfb-3; TGF-beta3; TGF-beta-3; Transforming growth factor; transforming growth factor beta 3; transforming growth factor beta precursor; transforming growth factor beta-3; Transforming growth factor beta-3 proprotein; transforming growth factor, beta 3; transforming growth factor-beta3