Oncostatin M Monoclonal Antibody (17001) | Invitrogen MA5-23810 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Oncostatin M Monoclonal Antibody (17001)

catalog :

MA5-23810

quantity :

100 ug

price :

US 414.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

17001

The same clone is also sold as:

R&D Systems: MAB295-100

reactivity :

human

application :

western blot, ELISA, neutralization

citations: 1

Reference
Tejedor S, Buigues M, Gonz xe1 lez King H, Silva A, Garc xed a N, Dekker N, et al. Oncostatin M-Enriched Small Extracellular Vesicles Derived from Mesenchymal Stem Cells Prevent Isoproterenol-Induced Fibrosis and Enhance Angiogenesis. Int J Mol Sci. 2023;24: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Oncostatin M Monoclonal Antibody (17001)

Catalog # :

MA5-23810

Quantity :

100 ug

Price :

US 414.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 0.1-0.4 ug/mL (Detection), 2-8 ug/mL (Capture), Neutralization: 0.5-2.0 ug/mL, Western Blot: 1 ug/mL

Species :

Human

Clone :

17001

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.

Immunogen :

E. coli-derived recombinant human Oncostatin M/OSM Ala26-Arg234

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 0.1-0.4 ug/mL (Detection), 2-8 ug/mL (Capture), Neutralization: 0.5-2.0 ug/mL, Western Blot: 1 ug/mL

Aliases :

MGC20461; OncoM; oncostatin M; oncostatin-M; OSM