OLIG1/OLIG2/OLIG3 Monoclonal Antibody (257224) | Invitrogen MA5-23805 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

OLIG1/OLIG2/OLIG3 Monoclonal Antibody (257224)

catalog :

MA5-23805

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

257224

The same clone is also sold as:

R&D Systems: IC2230P, MAB2230

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

citations: 1

Reference
Aslam N, Abusharieh E, Abuarqoub D, Ali D, Al Hattab D, Wehaibi S, et al. Anti-oncogenic activities exhibited by paracrine factors of MSCs can be mediated by modulation of KITLG and DKK1 genes in glioma SCs in vitro. Mol Ther Oncolytics. 2021;20:147-165 pubmed publisher

product information

Product Type :

Antibody

Product Name :

OLIG1/OLIG2/OLIG3 Monoclonal Antibody (257224)

Catalog # :

MA5-23805

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 8-25 ug/mL, Immunohistochemistry (Frozen): 8-25 ug/mL

Species :

Human

Clone :

257224

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Olig1 promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube. Olig2 is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.

Immunogen :

E. coli-derived recombinant human Olig1 (aa 1-272)

Format :

Lyophilized

Applications w/Dilutions :

Immunocytochemistry: 8-25 ug/mL, Immunohistochemistry (Frozen): 8-25 ug/mL

Aliases :

basic domain, helix-loop-helix protein, class B, 1; basic domain, helix-loop-helix protein, class B, 6; BHLHB1; bHLHb6; Bhlhb7; bHLHe19; bHLHe20; BHLHE21; class B basic helix-loop-helix protein 1; Class B basic helix-loop-helix protein 6; class B basic helix-loop-helix protein 7; Class E basic helix-loop-helix protein 19; class E basic helix-loop-helix protein 20; Class E basic helix-loop-helix protein 21; human protein kinase C-binding protein RACK17; OLIG1; OLIG2; olig-2; OLIG3; Oligo1; OLIGO2; Oligo2 antibody; Oligo3; oligodendrocyte lineage transcription factor 1; oligodendrocyte lineage transcription factor 2; oligodendrocyte transcription factor 1; Oligodendrocyte transcription factor 2; oligodendrocyte transcription factor 3; oligodendrocyte-specific bHLH transcription factor 1; oligodendrocyte-specific bHLH transcription factor 2; PRKCBP2; Protein kinase C-binding protein 2; Protein kinase C-binding protein RACK17; RACK17