This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IL-29 Monoclonal Antibody (247801)
catalog :
MA5-23791
quantity :
500 ug
price :
US 552.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
247801

The same clone is also sold as:
reactivity :
human
application :
neutralization
product information
Product Type :
Antibody
Product Name :
IL-29 Monoclonal Antibody (247801)
Catalog # :
MA5-23791
Quantity :
500 ug
Price :
US 552.00
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: 0.1-0.4 ug/mL (Detection), 2-8 ug/mL (Capture), Neutralization: 1-4 ug/mL
Species :
Human
Clone :
247801
Isotype :
IgG2a
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
IFN-lambdas constitute a novel family of interferons that mediate the induction of anti-viral protection in a wide variety of cells. There are three members in this family, namely lambda1, lambda2, and lambda3, which are also known as IL-29, IL-28A, and IL-28B, respectively. Similar to type I IFNs, IFN-lambdas activate an intracellular signaling to promote gene expression. IFN-lambdas mediate their anti-viral protection through a class II cytokine receptor complex composed of two essential receptor proteins, CRF2-12/IFN-lambdaR1, which is unique to IFN-lambdas, and CFR2-4/IL-10R2, which is shared with IL-10, IL-22, and IL-26 receptors. The IFN-lambdas, IL-28 and IL-29, have recently been reported to prime dendritic cells to induce proliferation of Foxp3-bearing regulatory T cells. DCs that differentiate in response to IFN-lambdas express high levels of class I and II MHC gene products, but low levels of costimulatory molecules. Moreover, these cells can specifically induce IL-2-dependent proliferation of CD4+CD25+FOXP3+ T cells with contact-dependent suppressive activity.
Immunogen :
Mouse myeloma cell line NS0-derived recombinant human IL-29/IFN-lambda 1 Gly20-Thr200
Format :
Lyophilized
Applications w/Dilutions :
ELISA: 0.1-0.4 ug/mL (Detection), 2-8 ug/mL (Capture), Neutralization: 1-4 ug/mL
Aliases :
cytokine Zcyto21; Cytokine Zcyto22; FNL1; IFN lambda1; IFNL1; IFNL3; IFN-lambda-1; IFN-lambda-3; IFN-lambda-4; IL28B; IL-28B; IL28C; IL-28C; IL29; IL-29; ILN; interferon lambda 1; interferon lambda 3; Interferon lambda1; interferon lambda-1; Interferon lambda-3; interferon, lambda 1; interferon, lambda 3; interferon, lambda 4; interferon-lambda-1; Interleukin; interleukin 29 (interferon, lambda 1); interleukin-28B; Interleukin-28C; interleukin-29; ZCYTO21; ZCYTO22
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA