Thrombopoietin Monoclonal Antibody (34817) | Invitrogen MA5-23731 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Thrombopoietin Monoclonal Antibody (34817)

catalog :

MA5-23731

quantity :

500 ug

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

34817

The same clone is also sold as:

R&D Systems: MAB288-100

reactivity :

human

application :

neutralization

product information

Product Type :

Antibody

Product Name :

Thrombopoietin Monoclonal Antibody (34817)

Catalog # :

MA5-23731

Quantity :

500 ug

Price :

US 484.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 0.1-2 ug/mL (Detection), 2-8 ug/mL (Capture), Neutralization: 5-10 ug/mL

Species :

Human

Clone :

34817

Isotype :

IgG2b

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.

Immunogen :

Sf 21-derived recombinant human Thrombopoietin/Tpo Ser22-Gly353

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 0.1-2 ug/mL (Detection), 2-8 ug/mL (Capture), Neutralization: 5-10 ug/mL

Aliases :

C-mpl ligand; Megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; megakaryocyte stimulating factor; Mgdf; MKCSF; ML; MPL ligand; Mpllg; MSA; Myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; TDH2A; THCYT1; THPO; Thrombopoietin; thyroid microsomal antigen; thyroid peroxidase; thyroperoxidase; Tpo; TPX