TIM-1 Monoclonal Antibody (219211), Alexa Fluor 488 | Invitrogen MA5-23634 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TIM-1 Monoclonal Antibody (219211), Alexa Fluor 488

catalog :

MA5-23634

quantity :

100 Tests

price :

US 432.00

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

219211

The same clone is also sold as:

R&D Systems: FAB1750G, MAB1750-100

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

TIM-1 Monoclonal Antibody (219211), Alexa Fluor 488

Catalog # :

MA5-23634

Quantity :

100 Tests

Price :

US 432.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL per million cells

Species :

Human

Clone :

219211

Isotype :

IgG2b

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail. The endogenous ligand for CD365 is Tim-4. In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus. The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes. Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity. CD365 has also been implicated in the T cell co-stimulation. CD365 is primarily expressed in epithelial cells. It is also highly expressed in A549, 769-P and Caco-2 and cell lines. CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.

Immunogen :

Mouse myeloma cell line NS0-derived recombinant human TIM-1/KIM-1/HAVCR Ser21-Thr288

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL per million cells

Aliases :

AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1