This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SPSB1 Monoclonal Antibody (3E7)
catalog :
MA5-22635
quantity :
100 ug
price :
US 474.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3.00E+07
reactivity :
human
product information
Product Type :
Antibody
Product Name :
SPSB1 Monoclonal Antibody (3E7)
Catalog # :
MA5-22635
Quantity :
100 ug
Price :
US 474.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: Assay-Dependent
Species :
Human
Clone :
3.00E+07
Isotype :
IgG2a, kappa
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:15601820, PubMed:21199876). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed:21199876). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (PubMed:21199876). [UniProt]
Immunogen :
SPSB1 (AAH15711, 1 a.a. ~ 273 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent
Aliases :
1110014L01Rik; 4930422J18Rik; AI596360; AI854583; CBG; fi35c01; hypothetical protein LOC334190; novel SPRY domain containing protein; RGD1309319; splA/ryanodine receptor domain and SOCS box containing 1; SPRY domain-containing SOCS box protein 1; SPRY domain-containing SOCS box protein SSB-1; Spsb1; SSB1; SSB-1; Unknown (protein for IMAGE:8228399); wu:fi35c01; zgc:114115
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA