PCDHGA10 Monoclonal Antibody (3A7) | Invitrogen MA5-22247 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PCDHGA10 Monoclonal Antibody (3A7)

catalog :

MA5-22247

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3A7

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

PCDHGA10 Monoclonal Antibody (3A7)

Catalog # :

MA5-22247

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Western Blot: 1-5 ug/mL

Species :

Human

Clone :

3A7

Isotype :

IgG2a, kappa

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Immunogen :

PCDHGA10 (NP_061736.1, 219 a.a. ~ 316 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Western Blot: 1-5 ug/mL

Aliases :

PCDHGA10; PCDH-gamma-A10; protocadherin gamma subfamily A, 10; protocadherin gamma-A10